Itinerary for 6 day trip to Medellín

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Here's an ideal itinerary for 6 days in Medellín:

Arrive in Medellín and check into your hotel
Start your day with a city tour to get a feel for the city and its history. Visit the Plaza Botero, which is home to 23 of Fernando Botero's sculptures, and the nearby Antioquia Museum, which houses a collection of Botero's paintings and sculptures, as well as other works by Colombian artists.
Take a cable car ride up to the Santo Domingo Savio Library, which is a symbol of the city's transformation and a great place to take in panoramic views of the city.
End your day with a visit to the Pueblito Paisa, a replica of a traditional Antioquian village that offers a glimpse into the region's culture and architecture.

Take a day trip to Guatapé, a charming town located about 2 hours from Medellín.
Climb the 740 steps to the top of El Peñol, a massive rock formation that offers stunning views of the surrounding landscape.
Explore the colorful streets of Guatapé, which are adorned with vibrant murals and decorated with zócalos, or baseboards, that depict scenes from the town's history and culture.
Take a boat ride on the nearby reservoir, which is dotted with small islands and offers a peaceful escape from the city.

Visit Comuna 13, a neighborhood that has undergone a remarkable transformation in recent years and is now a hub of street art and community activism.
Take a guided tour of the area to learn about its history and the social initiatives that have helped to revitalize it.
Head to Parque Arví, a nature reserve located on the outskirts of the city, for a hike or a picnic in the lush forest.

Take a coffee tour to learn about the process of growing and harvesting coffee, which is an important part of Colombia's economy and culture.
Visit a coffee farm and sample some of the region's best brews.
Head to Jardín, a picturesque town located about 3 hours from Medellín, to explore its colorful streets and colonial architecture.
Take a horseback ride through the surrounding countryside or visit the nearby Cueva del Esplendor, a stunning waterfall that cascades into a natural pool.

Visit Parque Explora, a science museum that offers interactive exhibits on topics ranging from physics to biology.
Check out the nearby Parque de los Deseos, a public space that hosts concerts and cultural events.
Head to the Botanical Garden, which is home to over 1,000 species of plants and animals, for a peaceful stroll or a picnic.

Spend your last day in Medellín exploring the city at your own pace.
Visit any sights you missed earlier in the week or simply relax and soak up the city's vibrant energy.
In the evening, head to one of Medellín's many restaurants or bars to enjoy some of the city's delicious cuisine and nightlife.

I hope this itinerary helps you plan your trip to Medellín!